Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

tert-Butyl (4-oxo-4-phenylbutyl)carbamate

  • CAS No. 116437-41-3

  • Cat. No. CS-M1642
  • Purity≥97%
  • MDL No.MFCD08060130

*For research and further manufacturing use only, not for direct human use.

tert-Butyl (4-oxo-4-phenylbutyl)carbamate|CS-M1642

Structure of 116437-41-3

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 116437-41-3
  • Cat. No. CS-M1642
  • Purity ≥97%
  • MDL No. MFCD08060130
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₅H₂₁NO₃
  • Molecular Weight 263.33
  • Synonym(s) (4-OXO-4-PHENYL-BUTYL)-CARBAMIC ACID TERT-BUTYL ESTER
  • SMILES O=C(OC(C)(C)C)NCCCC(C1=CC=CC=C1)=O

Description

tert-Butyl (4-oxo-4-phenylbutyl)carbamate serves as a stable, bench-ready synthon for the introduction of a β-keto ester-like motif bearing a pendant phenyl group. This carbamate functionality enables straightforward deprotection and functionalization under mild conditions, facilitating access to complex ketone-containing architectures in synthetic and medicinal chemistry workflows.

Application

tert-Butyl (4-oxo-4-phenylbutyl)carbamate serves as a stable, bench-friendly synthon for the introduction of a 4-oxo-4-phenylbutyl moiety in synthetic sequences. It functions as a protected precursor to β-keto amine intermediates, enabling reliable enolate formation and subsequent C–C bond construction. The carbamate group ensures good solubility and ease of purification, while the ketone functionality supports diverse transformations including reductive amination and nucleophilic addition, making it valuable in the synthesis of complex heterocycles and bioactive scaffolds.

Synthesis

  • Route1
    • In-stock
      1,1-Dimethylethyl 2-oxo-1-pyrrolidinecarboxylate|CS-0181165
      85909-08-6
    • null|null
      100-58-3
    • ~96%
    • In-stock
      tert-Butyl (4-oxo-4-phenylbutyl)carbamate|CS-M1642
      116437-41-3

    References

    • WO2006/44825 A2, ; Page/Page column 55 ; WO 2006/044825 A2
  • Route2

    References

    • Journal of the American Chemical Society, , vol. 128, # 7 p. 2224 - 2225
  • Route3
    • null|null
      108-86-1
    • In-stock
      1,1-Dimethylethyl 2-oxo-1-pyrrolidinecarboxylate|CS-0181165
      85909-08-6
    • ~%
    • In-stock
      tert-Butyl (4-oxo-4-phenylbutyl)carbamate|CS-M1642
      116437-41-3

    References

    • Journal of Organic Chemistry, , vol. 54, # 1 p. 228 - 234

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   55.4
  • LogP   3.1742
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   5

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 116437-41-3 sigma116437-41-3 manufacturer116437-41-3 price116437-41-3 structure116437-41-3 SDSbuy 116437-41-3116437-41-3 supplier116437-41-3 uses116437-41-3 molecular weightprice of 116437-41-3116437-41-3 chemical name formula of 116437-41-3
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label