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CS-W001157 4
Total: USD 88.00

3-(Bromomethyl)tetrahydro-2H-pyran

  • CAS No. 116131-44-3

  • Cat. No. CS-D0475
  • Purity≥98%
  • MDL No.MFCD08235012

*For research and further manufacturing use only, not for direct human use.

3-(Bromomethyl)tetrahydro-2H-pyran|CS-D0475

Structure of 116131-44-3

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General Information

  • CAS No. 116131-44-3
  • Cat. No. CS-D0475
  • Purity ≥98%
  • MDL No. MFCD08235012
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₁₁BrO
  • Molecular Weight 179.05
  • Synonym(s) 3-BroMoMethyl tetrahydropyran
  • SMILES BrCC1COCCC1

Description

3-(Bromomethyl)tetrahydro-2H-pyran delivers a reactive bromomethyl handle tethered to a stable tetrahydropyran ring, enabling efficient functionalization in carbohydrate mimicry and synthetic intermediates. This bench-stable reagent integrates readily into nucleophilic substitution cascades under mild conditions, facilitating the construction of complex heterocyclic architectures with predictable stereochemistry.

Application

3-(Bromomethyl)tetrahydro-2H-pyran serves as a versatile synthetic building block for introducing a reactive alkylating handle at the tetrahydropyranyl ring. The bromomethyl group enables efficient nucleophilic substitution reactions, facilitating the construction of complex ethers and heterocyclic scaffolds. Its bench-stable nature and compatibility with diverse functional groups make it ideal for medicinal chemistry applications and solid-phase synthesis workflows.

Safety Information

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GHS Pictogram :
GHS No : GHS05,GHS07
Signal Word : Danger
UN#: 3265
Class : 8
Packing Group : Ⅱ
Hazard Statements : H302-H314
Precautionary Statements : P260-P264-P270-P280-P301+P330+P331-P304+P340-P363-P405-P501

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Computational Chemistry Data

  • TPSA   9.23
  • LogP   1.8079
  • H_Acceptors   1
  • H_Donors   0
  • Rotatable_Bonds   1

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