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CS-W001157 4
Total: USD 88.00

3-Bromoquinolin-7-ol

  • CAS No. 1160949-99-4

  • Cat. No. CS-0041973
  • Purity≥95%
  • MDL No.MFCD18413578

*For research and further manufacturing use only, not for direct human use.

3-Bromoquinolin-7-ol|CS-0041973

Structure of 1160949-99-4

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General Information

  • CAS No. 1160949-99-4
  • Cat. No. CS-0041973
  • Purity ≥95%
  • MDL No. MFCD18413578
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₆BrNO
  • Molecular Weight 224.05
  • Synonym(s) None
  • SMILES OC1=CC=C2C=C(Br)C=NC2=C1

Description

3-Bromoquinolin-7-ol features a bromine atom at the 3-position and a hydroxyl group at the 7-position of the quinoline scaffold, enabling direct functionalization in cross-coupling reactions. This electron-deficient heterocycle offers enhanced reactivity for C–C bond formation under palladium catalysis, with the phenolic OH providing additional coordination potential. The compound exhibits bench-stable handling characteristics and facilitates efficient synthesis of biologically active scaffolds.

Application

3-Bromoquinolin-7-ol serves as a versatile building block in medicinal chemistry, enabling palladium-catalyzed cross-coupling reactions due to its stable bromo functionality and phenolic hydroxyl group. The molecule exhibits good bench stability and facilitates efficient derivatization in late-stage functionalization workflows, with the quinoline core providing a privileged scaffold for bioactive compound development.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS06
Signal Word : Danger
UN#: 2811
Class : 6.1
Packing Group : Ⅲ
Hazard Statements : H301+H311+H331
Precautionary Statements : P264-P270-P330-P405-P501

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Computational Chemistry Data

  • TPSA   33.12
  • LogP   2.7029
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   0

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