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Cbz-Gly-Pro-OH

  • CAS No. 1160-54-9

  • Cat. No. CS-0147302
  • Purity≥98%
  • MDL No.MFCD00037341

*For research and further manufacturing use only, not for direct human use.

Cbz-Gly-Pro-OH|CS-0147302

Structure of 1160-54-9

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General Information

  • CAS No. 1160-54-9
  • Cat. No. CS-0147302
  • Purity ≥98%
  • MDL No. MFCD00037341
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₅H₁₈N₂O₅
  • Molecular Weight 306.32
  • Synonym(s) None
  • SMILES O=C(O)[C@H]1N(C(CNC(OCC2=CC=CC=C2)=O)=O)CCC1

Description

Cbz-Gly-Pro-OH is a protected dipeptide intermediate featuring a carbobenzoxy (Cbz) group at the N-terminus and a proline residue with a free C-terminal carboxylic acid. This configuration enables direct incorporation into peptide synthesis workflows, offering enhanced solubility and stability under standard conditions. The Cbz moiety facilitates convenient deprotection via hydrogenolysis, streamlining access to target sequences.

Synthesis

  • Route1

    References

    • Tetrahedron Letters, , vol. 36, # 12 p. 2105 - 2108
  • Route2
    • null|null
      173459-80-8
    • L-Proline Enalapril  Impurity|CS-0229432
      147-85-3
    • ~84%
    • In-stock
      Cbz-Gly-Pro-OH|CS-0147302
      1160-54-9

    References

    • Chemistry - A European Journal, , vol. 18, # 9 p. 2632 - 2638
  • Route3

    References

    • Chemistry of Natural Compounds, , vol. 26, # 6 p. 686 - 690 Khimiya Prirodnykh Soedinenii, , # 6 p. 805 - 810

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   95.94
  • LogP   0.9884
  • H_Acceptors   4
  • H_Donors   2
  • Rotatable_Bonds   5

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