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CS-W001157 4
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Piperidine-4-carbaldehydehydrochloride

  • CAS No. 1159825-32-7

  • Cat. No. CS-0171609
  • Purity≥95%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

Piperidine-4-carbaldehydehydrochloride|CS-0171609

Structure of 1159825-32-7

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General Information

  • CAS No. 1159825-32-7
  • Cat. No. CS-0171609
  • Purity ≥95%
  • MDL No. None
  • Storage -20°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₁₂ClNO
  • Molecular Weight 149.62
  • Synonym(s) Piperidine-4-carbaldehyde hydrochloride
  • SMILES C1CNCCC1C=O.Cl

Description

Piperidine-4-carbaldehyde hydrochloride delivers a reactive aldehyde handle within a stable, bench-ready heterocyclic framework. This moisture-tolerant derivative integrates readily into synthetic sequences requiring electrophilic functionality at the C4 position of piperidine. The hydrochloride salt enhances solubility and handling in aqueous or polar organic media, streamlining use in medicinal chemistry and process development workflows.

Application

Piperidine-4-carbaldehyde hydrochloride serves as a versatile building block in medicinal chemistry, enabling efficient access to diverse heterocyclic scaffolds. Its aldehyde functionality facilitates reductive amination, Grignard additions, and condensation reactions under standard conditions. The hydrochloride salt enhances bench stability and simplifies handling, while maintaining compatibility with common protecting group strategies. This compound functions effectively in the synthesis of bioactive molecules requiring piperidine-based cores.

Safety Information

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GHS Pictogram : N/A
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Signal Word : N/A
UN#: N/A
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Packing Group : N/A
Hazard Statements : N/A
Precautionary Statements : N/A

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Computational Chemistry Data

  • TPSA   29.1
  • LogP   0.6067
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   1

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