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CS-W001157 4
Total: USD 88.00

5-Methoxyisoindoline hydrochloride

  • CAS No. 1159822-61-3

  • Cat. No. CS-W006624
  • Purity≥98%
  • MDL No.MFCD09997806

*For research and further manufacturing use only, not for direct human use.

5-Methoxyisoindoline hydrochloride|CS-W006624

Structure of 1159822-61-3

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General Information

  • CAS No. 1159822-61-3
  • Cat. No. CS-W006624
  • Purity ≥98%
  • MDL No. MFCD09997806
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₁₂ClNO
  • Molecular Weight 185.65
  • Synonym(s) 5-Methoxy-2,3-dihydro-1H-isoindole hydrochloride
  • SMILES COC1=CC=C2CNCC2=C1.Cl

Description

5-Methoxyisoindoline hydrochloride is a bench-stable, moisture-tolerant heterocyclic amine featuring a methoxy group at the 5-position that enhances electron density and solubility. This derivative integrates readily into synthetic routes for bioactive molecules, offering improved handling over unsubstituted analogs.

Application

5-Methoxyisoindoline hydrochloride serves as a stable, bench-ready building block for the synthesis of isoindoline-based pharmaceutical intermediates. Its well-defined reactivity enables efficient functionalization at the nitrogen and aromatic positions, facilitating diverse coupling reactions and heterocycle construction. The hydrochloride salt enhances solubility and handling, supporting straightforward purification and compatibility with standard synthetic workflows.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   21.26
  • LogP   1.7202
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   1

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