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CS-W001157 4
Total: USD 88.00

7-Bromo-2-methyl-[1,2,4]triazolo[1,5-a]pyridine

  • CAS No. 1159812-31-3

  • Cat. No. CS-W006776
  • Purity≥95%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

7-Bromo-2-methyl-[1,2,4]triazolo[1,5-a]pyridine|CS-W006776

Structure of 1159812-31-3

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General Information

  • CAS No. 1159812-31-3
  • Cat. No. CS-W006776
  • Purity ≥95%
  • MDL No. None
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₆BrN₃
  • Molecular Weight 212.05
  • Synonym(s) 6-Tributylstannyl[1,2,4]triazolo[1,5-a]pyridine
  • SMILES CC1=NN2C=CC(Br)=CC2=N1

Description

7-Bromo-2-methyl-[1,2,4]triazolo[1,5-a]pyridine features a rigid heterocyclic core with complementary electron-deficient and alkyl substituents. This scaffold enables direct incorporation into medicinal chemistry libraries, serving as a key building block for kinase inhibitors and bioactive small molecules. The bromo group facilitates late-stage functionalization via cross-coupling reactions.

Application

7-Bromo-2-methyl-[1,2,4]triazolo[1,5-a]pyridine serves as a versatile building block in medicinal chemistry, enabling efficient construction of heterocyclic scaffolds via palladium-catalyzed cross-coupling reactions. The bromo group facilitates reliable C–H functionalization, while the methyl substituent enhances solubility and modulates electronic properties. Its bench-stable nature and compatibility with standard coupling conditions make it ideal for iterative synthesis of bioactive compounds.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   30.19
  • LogP   1.80022
  • H_Acceptors   3
  • H_Donors   0
  • Rotatable_Bonds   0

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