1-(1-Methyl-1H-indazol-5-yl)ethan-1-one

Name: 1-(1-Methyl-1H-indazol-5-yl)ethan-1-one
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 1159511-24-6
Cat. No. CS-0044886
Molecule weight174.20
Purity≥98%
MDL No.MFCD11869767

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

1-(1-Methyl-1H-indazol-5-yl)ethan-1-one|CS-0044886

Structure of 1159511-24-6

Size

Price

Quantity

* Please select Quantity before adding items.

General Information

CAS No. 1159511-24-6
Cat. No. CS-0044886
Purity ≥98%
MDL No. MFCD11869767
Storage Store at room temperature
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₁₀H₁₀N₂O
Molecular Weight 174.20
Synonym(s) 1-(1-Methyl-1H-indazol-5-yl)ethanone
SMILES CC(C1=CC2=C(N(C)N=C2)C=C1)=O

Description

1-(1-Methyl-1H-indazol-5-yl)ethan-1-one features a fused bicyclic indazolyl core linked to a methyl ketone group, delivering a robust scaffold for medicinal chemistry. This bench-stable compound integrates readily into synthetic routes targeting kinase inhibitors and bioactive heterocycles. The electron-deficient carbonyl enables nucleophilic addition and conjugate functionalization under mild conditions.

Application

1-(1-Methyl-1H-indazol-5-yl)ethan-1-one serves as a versatile building block for indazolyl ketones, enabling direct functionalization at the C5 position. Its stability and compatibility with standard synthetic protocols facilitate efficient derivatization in medicinal chemistry workflows. The methyl-substituted indazole core provides a rigid, planar scaffold suitable for structure-activity studies. Functions effectively in nucleophilic additions, reductive aminations, and transition-metal-catalyzed coupling reactions, offering practical utility in the construction of heterocyclic drug candidates.

Synthesis

Route1
- 1334405-49-0
- ~%
- In-stock
  
  1159511-24-6
References
- Leonard, Kristi Anne; Zhang, Yan; Tounge, Brett Andrew; Wang, Aihua; Hawkins, Michael; Jackson, Paul Francis; Barbay, Joseph Kent; Maharoof, Umar S.M. Patent: US2012/129872 A1, 2012 ; Location in patent: Page/Page column 22-23 ;
Route2
- In-stock
  
  872607-89-1
- ~%
- In-stock
  
  1159511-24-6
References
- Leonard, Kristi Anne; Zhang, Yan; Tounge, Brett Andrew; Wang, Aihua; Hawkins, Michael; Jackson, Paul Francis; Barbay, Joseph Kent; Maharoof, Umar S.M. Patent: US2012/129872 A1, 2012 ;

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

TPSA 34.89
LogP 1.7759
H_Acceptors 3
H_Donors 0
Rotatable_Bonds 1

Other Classifications

Building Blocks Skeleton Aromatic heterocycle compounds Indazole compounds

Key Words

1-(1-Methyl-1H-indazol-5-yl)ethan-1-one sigma1-(1-Methyl-1H-indazol-5-yl)ethan-1-one manufacturer1-(1-Methyl-1H-indazol-5-yl)ethan-1-one price1-(1-Methyl-1H-indazol-5-yl)ethan-1-one structure1-(1-Methyl-1H-indazol-5-yl)ethan-1-one SDSbuy 1-(1-Methyl-1H-indazol-5-yl)ethan-1-one1-(1-Methyl-1H-indazol-5-yl)ethan-1-one supplier1-(1-Methyl-1H-indazol-5-yl)ethan-1-one uses1-(1-Methyl-1H-indazol-5-yl)ethan-1-one molecular weightprice of 1-(1-Methyl-1H-indazol-5-yl)ethan-1-one1-(1-Methyl-1H-indazol-5-yl)ethan-1-one chemical name formula of 1-(1-Methyl-1H-indazol-5-yl)ethan-1-one

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

1-(1-Methyl-1H-indazol-5-yl)ethan-1-one

CAS No. 1159511-24-6

Recommended Products