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(R)-1-Methylpiperidin-3-amine dihydrochloride

  • CAS No. 1157849-50-7

  • Cat. No. CS-0053341
  • Molecule weight187.11
  • Purity≥95%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

(R)-1-Methylpiperidin-3-amine dihydrochloride|CS-0053341

Structure of 1157849-50-7

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General Information

  • CAS No. 1157849-50-7
  • Cat. No. CS-0053341
  • Purity ≥95%
  • MDL No. None
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₁₆Cl₂N₂
  • Molecular Weight 187.11
  • Synonym(s) (3R)-1-methylpiperidin-3-amine dihydrochloride
  • SMILES Cl.Cl.CN1CCC[C@@H](N)C1

Description

(R)-1-Methylpiperidin-3-amine dihydrochloride is a bench-stable, moisture-tolerant chiral amine scaffold featuring a tertiary amine center and a stereogenic carbon. This configuration enables selective incorporation into bioactive molecules, particularly in medicinal chemistry campaigns targeting CNS disorders. The dihydrochloride salt enhances solubility and handling under standard conditions.

Application

(R)-1-Methylpiperidin-3-amine dihydrochloride serves as a chiral building block for medicinal chemistry and catalyst development, offering a readily accessible secondary amine with defined stereochemistry. Its stability in air and moisture facilitates handling, while the protonated amine enables efficient salt formation and purification. The molecule functions as a versatile scaffold in the synthesis of bioactive molecules, particularly in the construction of piperidine-based pharmaceuticals and asymmetric ligands.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   29.26
  • LogP   0.8829
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   0

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