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CS-W001157 4
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6-Bromo-5-methyl-3,4-dihydro-2H-benzo[b][1,4]oxazine

  • CAS No. 1154740-48-3

  • Cat. No. CS-0187192
  • Purity≥96%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

6-Bromo-5-methyl-3,4-dihydro-2H-benzo[b][1,4]oxazine|CS-0187192

Structure of 1154740-48-3

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General Information

  • CAS No. 1154740-48-3
  • Cat. No. CS-0187192
  • Purity ≥96%
  • MDL No. None
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₁₀BrNO
  • Molecular Weight 228.09
  • Synonym(s) 6-Bromo-5-methyl-3,4-dihydro-2H-benzo[1,4]oxazine
  • SMILES CC1=C2C(=CC=C1Br)OCCN2

Description

6-Bromo-5-methyl-3,4-dihydro-2H-benzo[b][1,4]oxazine features a brominated heterocyclic core with a methyl substituent at the 5-position, offering enhanced reactivity for cross-coupling and functionalization. The dihydrooxazine scaffold provides structural rigidity and compatibility with transition-metal catalyzed transformations under standard conditions.

Application

6-Bromo-5-methyl-3,4-dihydro-2H-benzo[b][1,4]oxazine serves as a versatile building block for the synthesis of bioactive heterocycles. Its bromine functionality enables palladium-catalyzed cross-coupling reactions, while the methyl group provides steric and electronic modulation. The dihydrooxazine core offers stability and compatibility with standard synthetic protocols, facilitating efficient access to substituted benzoxazines used in medicinal chemistry and materials science.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302
Precautionary Statements : P264-P270-P330-P501

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Computational Chemistry Data

  • TPSA   21.26
  • LogP   2.56182
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   0

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