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Structure of 1147558-13-1
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4-(Cyclopropanesulfonyl)aniline features a cyclopropanesulfonyl group attached to an aniline scaffold, delivering enhanced metabolic stability and tunable polarity. This combination enables efficient incorporation into bioactive scaffolds and facilitates direct coupling in late-stage functionalization workflows under mild conditions.
4-(Cyclopropanesulfonyl)aniline serves as a versatile building block for sulfonamide-containing scaffolds in medicinal chemistry. The cyclopropanesulfonyl group provides enhanced metabolic stability and modulates lipophilicity, while the aniline functionality enables direct coupling reactions, electrophilic substitution, and amide formation. Bench-stable and readily purified by chromatography or crystallization, it functions effectively in both solution-phase and solid-phase synthesis workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302
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Precautionary Statements : P264-P270-P330-P501
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Lot numbers can be found on the outside label of a product: