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Structure of 114676-61-8
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tert-Butyl (2S,4R)-4-hydroxy-2-methylpyrrolidine-1-carboxylate is a stereochemically defined pyrrolidine derivative featuring a bench-stable tert-butyl carbamate protecting group and a chiral hydroxyl moiety. This configuration enables selective transformations in asymmetric synthesis, particularly in the construction of bioactive heterocycles where precise stereocontrol is essential. The molecule integrates readily into complex scaffolds due to its stability under standard conditions and compatibility with diverse reaction protocols.
tert-Butyl (2S,4R)-4-hydroxy-2-methylpyrrolidine-1-carboxylate serves as a stereochemically defined chiral building block for the synthesis of pyrrolidine-based pharmaceuticals and natural products. The protected hydroxyl group enables selective transformations, while the tert-butyl carbamate facilitates easy deprotection under mild acidic conditions. Its configurational stability and compatibility with standard coupling reactions make it valuable in iterative synthetic sequences and medicinal chemistry campaigns.
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: