2-Fluoro-4-nitrobenzene-1-sulfonyl chloride

Name: 2-Fluoro-4-nitrobenzene-1-sulfonyl chloride
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 1146290-36-9
Cat. No. CS-0157164
Purity≥97%
MDL No.MFCD11858095

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

2-Fluoro-4-nitrobenzene-1-sulfonyl chloride|CS-0157164

Structure of 1146290-36-9

Size

Price

Quantity

* Please select Quantity before adding items.

Description

2-Fluoro-4-nitrobenzene-1-sulfonyl chloride features a fluorine atom at the ortho position and a nitro group at the para position relative to the sulfonyl chloride, creating an electron-deficient aryl system. This combination enhances reactivity in nucleophilic aromatic substitution processes. The sulfonyl chloride moiety enables efficient coupling with amines and alcohols under mild conditions, facilitating the synthesis of sulfonamide and sulfonate derivatives. The molecule exhibits good bench stability and moisture tolerance, simplifying handling in synthetic workflows.

Application

2-Fluoro-4-nitrobenzene-1-sulfonyl chloride serves as a versatile sulfonylating agent for the synthesis of sulfonamide derivatives, enabling efficient functionalization of amines under mild conditions. Its electron-withdrawing nitro and fluorine substituents enhance reactivity while maintaining bench stability, facilitating clean reactions with broad functional group tolerance. The compound is particularly valuable in constructing heterocyclic scaffolds and bioactive intermediates common in medicinal chemistry workflows.

General Information

CAS No. 1146290-36-9
Cat. No. CS-0157164
Purity ≥97%
MDL No. MFCD11858095
Storage Store at room temperature
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₆H₃ClFNO₄S
Molecular Weight 239.61
Synonym(s) None
SMILES C1=CC(=C(C=C1[N+](=O)[O-])F)S(=O)(=O)Cl

Computational Chemistry Data

TPSA 77.28
LogP 1.6614
H_Acceptors 4
H_Donors 0
Rotatable_Bonds 2

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS05
Signal Word : Danger	UN#: 3261
Class : 8	Packing Group : Ⅲ
Hazard Statements : H302-H314
Precautionary Statements : P260-P264-P280-P301+P330+P331-P303+P361+P353-P304+P340-P305+P351+P338-P363-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Other Classifications

Building Blocks Functional Group Sulfonyl Chloride

Building Blocks Functional Group Nitro compounds

Building Blocks Skeleton Aromatic ring compounds Benzene compounds

Key Words

1146290-36-9 sigma1146290-36-9 manufacturer1146290-36-9 price1146290-36-9 structure1146290-36-9 SDSbuy 1146290-36-91146290-36-9 supplier1146290-36-9 uses1146290-36-9 molecular weightprice of 1146290-36-91146290-36-9 chemical name formula of 1146290-36-9

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

2-Fluoro-4-nitrobenzene-1-sulfonyl chloride

CAS No. 1146290-36-9

Recommended Products