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Structure of 114525-81-4
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This (R)-configured thiomorpholine derivative features a bench-stable tert-butyl carbamate protecting group and a carboxylic acid handle, enabling straightforward incorporation into peptide couplings and macrocyclization reactions under standard conditions.
(R)-4-(tert-Butoxycarbonyl)thiomorpholine-3-carboxylic acid serves as a valuable chiral building block for the synthesis of sulfonamide-containing heterocycles and peptidomimetics. The tert-butyl ester group provides excellent bench stability and facilitates straightforward deprotection under mild acidic conditions. Its well-defined stereochemistry enables precise control in asymmetric synthesis, while the thiomorpholine scaffold offers enhanced metabolic stability and conformational rigidity in bioactive molecule design.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: