4-(Aminomethyl)-3-(trifluoromethyl)benzonitrile

Name: 4-(Aminomethyl)-3-(trifluoromethyl)benzonitrile
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 1141894-75-8
Cat. No. CS-0133680
Purity≥95%
MDL No.None

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

4-(Aminomethyl)-3-(trifluoromethyl)benzonitrile|CS-0133680

Structure of 1141894-75-8

Size

Price

Quantity

* Please select Quantity before adding items.

Description

4-(Aminomethyl)-3-(trifluoromethyl)benzonitrile features a trifluoromethyl group that enhances metabolic stability and lipophilicity, while the nitrile moiety provides a polar handle for downstream functionalization. This scaffold integrates readily into bioactive molecule design, particularly in kinase inhibitors and pharmaceutical intermediates.

Application

4-(Aminomethyl)-3-(trifluoromethyl)benzonitrile serves as a versatile building block in medicinal chemistry, enabling the construction of bioactive heterocycles and pharmaceutical scaffolds. Its trifluoromethyl group enhances metabolic stability and lipophilicity, while the nitrile and primary amine functionalities provide orthogonal handles for downstream derivatization. The compound exhibits good bench stability and is compatible with standard coupling and cyclization protocols, facilitating efficient access to complex target molecules.

General Information

CAS No. 1141894-75-8
Cat. No. CS-0133680
Purity ≥95%
MDL No. None
Storage 4°C, protect from light
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₉H₇F₃N₂
Molecular Weight 200.16
Synonym(s) 4-Aminomethyl-3-trifluoromethyl-benzonitrile
SMILES N#CC1=CC=C(CN)C(C(F)(F)F)=C1

Computational Chemistry Data

TPSA 49.81
LogP 2.03578
H_Acceptors 2
H_Donors 1
Rotatable_Bonds 1

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302
Precautionary Statements : P264-P270-P330-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Other Classifications

Building Blocks Functional Group Fluoride

Building Blocks Functional Group Cyanide/Nitrile

Building Blocks Skeleton Aromatic ring compounds Benzene compounds

Key Words

1141894-75-8 sigma1141894-75-8 manufacturer1141894-75-8 price1141894-75-8 structure1141894-75-8 SDSbuy 1141894-75-81141894-75-8 supplier1141894-75-8 uses1141894-75-8 molecular weightprice of 1141894-75-81141894-75-8 chemical name formula of 1141894-75-8

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

4-(Aminomethyl)-3-(trifluoromethyl)benzonitrile

CAS No. 1141894-75-8

Recommended Products