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Structure of 1141878-45-6
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This boronate moiety integrates a tetrahydro-2H-pyran-2-yl protected pyrazole scaffold with a trifluoromethyl group, offering enhanced stability and orthogonal deprotection compatibility. The electron-deficient pyrazole core enables efficient Suzuki-Miyaura coupling under standard conditions, while the bench-stable, moisture-tolerant structure simplifies handling in synthetic workflows.
(1-(Tetrahydro-2H-pyran-2-yl)-3-(trifluoromethyl)-1H-pyrazol-5-yl)boronic acid serves as a stable, bench-ready building block for Suzuki-Miyaura cross-coupling reactions. The tetrahydro-2H-pyran-2-yl protecting group ensures excellent shelf stability and facilitates selective deprotection under mild acidic conditions. Its trifluoromethyl-substituted pyrazole core provides enhanced metabolic stability and favorable electronic properties, making it particularly valuable in the synthesis of functionalized heterocyclic scaffolds for medicinal chemistry applications.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: