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Structure of 114012-42-9
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3-Phenyloxetane-3-carboxylic acid features a strained oxetane ring fused to a phenyl group and a carboxylic acid moiety, enabling efficient cycloaddition reactions. This structural motif delivers high reactivity in bioorthogonal labeling and polymer functionalization under physiological conditions. The carboxylic acid facilitates conjugation via amine coupling or esterification.
3-Phenyloxetane-3-carboxylic acid serves as a stable, bench-ready building block for the synthesis of bioactive heterocycles and pharmaceutical intermediates. Its oxetane ring imparts high reactivity in nucleophilic additions and facilitates metabolic stability in drug candidates. The carboxylic acid group enables direct derivatization via standard coupling reactions, while the phenyl substituent enhances solubility and provides a handle for further functionalization. Functions effectively in both small-molecule discovery and process-scale applications.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: