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CS-W001157 4
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Methyl 6-oxospiro[3.3]heptane-2-carboxylate

  • CAS No. 1138480-98-4

  • Cat. No. CS-0048921
  • Purity≥97%
  • MDL No.MFCD20922770

*For research and further manufacturing use only, not for direct human use.

Methyl 6-oxospiro[3.3]heptane-2-carboxylate|CS-0048921

Structure of 1138480-98-4

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General Information

  • CAS No. 1138480-98-4
  • Cat. No. CS-0048921
  • Purity ≥97%
  • MDL No. MFCD20922770
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₁₂O₃
  • Molecular Weight 168.19
  • Synonym(s) None
  • SMILES O=C(OC)C1CC2(CC(=O)C2)C1

Description

Methyl 6-oxospiro[3.3]heptane-2-carboxylate features a rigid spirocyclic core with a ketone at the bridgehead and an ester group, enabling direct functionalization at C6. This configuration supports efficient access to polycyclic scaffolds through tandem cyclizations and asymmetric transformations under mild conditions.

Application

Methyl 6-oxospiro[3.3]heptane-2-carboxylate serves as a versatile bicyclic building block for the synthesis of complex carbocyclic and heterocyclic frameworks. The spirocyclic core provides rigidity and defined stereochemistry, while the ketone and ester functionalities enable sequential functionalization via enolate chemistry, nucleophilic addition, and reduction. Its bench-stable nature and compatibility with standard synthetic protocols facilitate efficient access to medicinally relevant scaffolds in natural product and medicinal chemistry applications.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319
Precautionary Statements : P264-P270-P280-P302+P352-P330-P362+P364-P501

Quality Control

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Computational Chemistry Data

  • TPSA   43.37
  • LogP   0.9187
  • H_Acceptors   3
  • H_Donors   0
  • Rotatable_Bonds   1

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