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CS-W001157 4
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1-(3-Bromo-4-methoxyphenyl)methanamine hydrochloride

  • CAS No. 1134716-28-1

  • Cat. No. CS-0241473
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

1-(3-Bromo-4-methoxyphenyl)methanamine hydrochloride|CS-0241473

Structure of 1134716-28-1

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General Information

  • CAS No. 1134716-28-1
  • Cat. No. CS-0241473
  • Purity ≥98%
  • MDL No. None
  • Storage Store at room temperature, keep dry and cool
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₁₁BrClNO
  • Molecular Weight 252.54
  • Synonym(s) None
  • SMILES NCC1=CC=C(OC)C(Br)=C1.[H]Cl

Description

This bench-stable amine derivative features a brominated methoxyphenyl scaffold, enabling direct coupling in cross-coupling reactions. The hydrochloride salt enhances solubility and stability, simplifying handling in synthetic workflows.

Application

1-(3-Bromo-4-methoxyphenyl)methanamine hydrochloride serves as a versatile building block for medicinal chemistry and process development, enabling efficient construction of biologically relevant scaffolds. The bromo group facilitates palladium-catalyzed cross-coupling reactions, while the methoxy substituent provides moderate electron donation and enhances solubility. The amine functionality, delivered as a stable hydrochloride salt, offers excellent handling properties and compatibility with standard functional group manipulations. Its bench-stable nature supports reliable use in multi-step syntheses and API intermediate development.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   35.25
  • LogP   2.3382
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   2

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