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CS-W001157 4
Total: USD 88.00

2-Formyl-4-methoxyphenylboronic acid pinacol ester

  • CAS No. 1132669-90-9

  • Cat. No. CS-0190016
  • Purity≥96%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

2-Formyl-4-methoxyphenylboronic acid pinacol ester|CS-0190016

Structure of 1132669-90-9

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General Information

  • CAS No. 1132669-90-9
  • Cat. No. CS-0190016
  • Purity ≥96%
  • MDL No. None
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₄H₁₉BO₄
  • Molecular Weight 262.11
  • Synonym(s) 5-Methoxy-2-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)benzaldehyde
  • SMILES CC1(C)C(C)(C)OB(C2=CC=C(C=C2C=O)OC)O1

Description

2-Formyl-4-methoxyphenylboronic acid pinacol ester features a stable boronate ester moiety paired with an aldehyde-functionalized aromatic ring, enabling efficient Suzuki-Miyaura coupling under mild conditions. The methoxy group enhances solubility and electron density, while the pinacol protection ensures bench-stable handling and compatibility with diverse reaction environments.

Application

2-Formyl-4-methoxyphenylboronic acid pinacol ester serves as a stable, bench-ready building block for Suzuki-Miyaura coupling reactions. The pinacol boronate ester enables efficient C–C bond formation under mild conditions, with the aldehyde group offering orthogonal reactivity for downstream functionalization. Its compatibility with diverse reaction partners and ease of purification make it a practical choice for constructing complex aromatic scaffolds in medicinal chemistry and materials synthesis.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   44.76
  • LogP   1.8069
  • H_Acceptors   4
  • H_Donors   0
  • Rotatable_Bonds   3

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