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Structure of 1131615-04-7
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3-Bromo-4-(difluoromethyl)benzoic acid features a strategically positioned difluoromethyl group that enhances metabolic stability and modulates electronic properties. The bromo substituent enables facile downstream functionalization via cross-coupling reactions. This aryl halide integrates efficiently into pharmaceutical scaffolds, offering improved lipophilicity and bioavailability profiles under standard conditions.
3-Bromo-4-(difluoromethyl)benzoic acid serves as a versatile building block for medicinal chemistry and materials synthesis, enabling direct incorporation of both bromine and difluoromethyl functionalities into target molecules. The carboxylic acid group facilitates derivatization via standard amide, ester, or acyl halide transformations, while the ortho-bromine supports palladium-catalyzed cross-coupling reactions. Its bench-stable crystalline form ensures reliable handling and purification in multi-step synthetic sequences.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H320-H335
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Precautionary Statements : P264-P270-P330
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Lot numbers can be found on the outside label of a product: