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Structure of 1131223-44-3
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2-Methyl-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3,4-dihydroisoquinolin-1(2H)-one features a boronate ester handle integrated into a sterically hindered dihydroisoquinolinone scaffold. This structure enables efficient Suzuki-Miyaura coupling under standard conditions, delivering complex heterocyclic architectures with high functional group tolerance. The tetramethyl-substituted dioxaborolane moiety ensures excellent stability and moisture resistance during handling.
2-Methyl-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3,4-dihydroisoquinolin-1(2H)-one serves as a versatile boronate building block for Suzuki-Miyaura coupling reactions. The dihydroisoquinolinone core provides structural rigidity and functional group tolerance, enabling efficient late-stage diversification in medicinal chemistry. Bench-stable and readily purified by flash chromatography, it facilitates the construction of complex heterocyclic scaffolds common in pharmaceutical development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319
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Precautionary Statements : P264-P270-P280-P302+P352-P330-P362+P364-P501
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Lot numbers can be found on the outside label of a product: