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Morpholinium, 4-(4,6-dimethoxy-1,3,5-triazin-2-yl)-4-methyl-, hexafluorophosphate(1-) (1:1)

  • CAS No. 1129971-87-4

  • Cat. No. CS-1268154
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

Morpholinium, 4-(4,6-dimethoxy-1,3,5-triazin-2-yl)-4-methyl-, hexafluorophosphate(1-) (1:1)|CS-1268154

Structure of 1129971-87-4

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General Information

  • CAS No. 1129971-87-4
  • Cat. No. CS-1268154
  • Purity ≥98%
  • MDL No. None
  • Storage 4°C, protect from light, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₁₇F₆N₄O₃P
  • Molecular Weight 386.23
  • Synonym(s) None
  • SMILES [F-][P+5]([F-])([F-])([F-])([F-])[F-].COC1=NC(OC)=NC([N+]2(CCOCC2)C)=N1

Description

This morpholinium reagent features a reactive 4,6-dimethoxy-1,3,5-triazin-2-yl group paired with a hexafluorophosphate counterion, enabling efficient coupling under mild conditions. The electron-deficient triazine moiety facilitates rapid activation of nucleophiles, while the morpholinium cation enhances solubility in organic solvents. This combination delivers high functional group tolerance and predictable reaction kinetics in peptide and oligonucleotide synthesis workflows.

Application

Morpholinium, 4-(4,6-dimethoxy-1,3,5-triazin-2-yl)-4-methyl-, hexafluorophosphate(1-) (1:1) serves as a highly effective coupling reagent in amide and ester bond formation. Its robust reactivity enables efficient activation of carboxylic acids under mild conditions, with excellent functional group tolerance and clean byproduct formation. The morpholinium moiety enhances solubility and stability, while the hexafluorophosphate counterion facilitates easy purification. Ideal for peptide synthesis and small-molecule derivatization workflows.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   N/A
  • LogP   N/A
  • H_Acceptors   N/A
  • H_Donors   N/A
  • Rotatable_Bonds   N/A

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