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CS-W001157 4
Total: USD 88.00

(((9H-Fluoren-9-yl)methoxy)carbonyl)-D-tyrosine

  • CAS No. 112883-29-1

  • Cat. No. CS-0101017
  • Purity≥95%
  • MDL No.MFCD00171384

*For research and further manufacturing use only, not for direct human use.

(((9H-Fluoren-9-yl)methoxy)carbonyl)-D-tyrosine|CS-0101017

Structure of 112883-29-1

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General Information

  • CAS No. 112883-29-1
  • Cat. No. CS-0101017
  • Purity ≥95%
  • MDL No. MFCD00171384
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₂₄H₂₁NO₅
  • Molecular Weight 403.43
  • Synonym(s) None
  • SMILES OC(C=C1)=CC=C1C[C@H](C(O)=O)NC(OCC2C3=C(C4=C2C=CC=C4)C=CC=C3)=O

Description

Fmoc-D-Tyr-OH is a bench-stable, moisture-tolerant amino acid derivative featuring a fluorenylmethoxycarbonyl protecting group that enables efficient solid-phase peptide synthesis. This configuration enhances solubility and minimizes racemization during coupling steps, streamlining the incorporation of D-tyrosine into complex peptide architectures.

Synthesis

  • Route1
    • In-stock
      Fmoc-Osu Amino acid impurity|CS-1733136
      82911-69-1
    • L-Tyrosine Levodopa Impurity|CS-0229709
      60-18-4
    • ~86%
    • In-stock
      (((9H-Fluoren-9-yl)methoxy)carbonyl)-D-tyrosine|CS-0101017
      112883-29-1

    References

    • Djedaini-Pilard, Florence; Azaroual-Bellanger, Nathalie; Gosnat, Muriel; Vernet, Delphine; Perly, Bruno Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), 1995 , # 4 p. 723 - 730
  • Route2

    References

    • Roviello, Giovanni N.; Musumeci, Domenica; Bucci, Enrico M.; Pedone, Carlo International Journal of Pharmaceutics, 2011 , vol. 415, # 1-2 p. 206 - 210
  • Route3

    References

    • WO2006/37113 A2, ; Page/Page column title page; 5; 13; 14; 24; sheet 5 ;

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   95.86
  • LogP   3.9266
  • H_Acceptors   4
  • H_Donors   3
  • Rotatable_Bonds   6

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