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CS-W001157 4
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(2R,3S)-tert-Butyl 6-oxo-2,3-diphenylmorpholine-4-carboxylate

  • CAS No. 112741-49-8

  • Cat. No. CS-W002317
  • Purity≥96%
  • MDL No.MFCD00074955

*For research and further manufacturing use only, not for direct human use.

(2R,3S)-tert-Butyl 6-oxo-2,3-diphenylmorpholine-4-carboxylate|CS-W002317

Structure of 112741-49-8

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General Information

  • CAS No. 112741-49-8
  • Cat. No. CS-W002317
  • Purity ≥96%
  • MDL No. MFCD00074955
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₂₁H₂₃NO₄
  • Molecular Weight 353.41
  • Synonym(s) tert-butyl (2S,3S)-6-oxo-2,3-diphenylmorpholine-4-carboxylate
  • SMILES O=C(N1[C@@H](C2=CC=CC=C2)[C@@H](C3=CC=CC=C3)OC(C1)=O)OC(C)(C)C

Synthesis

  • Route1
    • Ethyl 2-((Tert-butoxycarbonyl)((1S,2R)-2-hydroxy-1,2-diphenylethyl)amino)acetate|CS-0765536
      112741-70-5
    • ~73%
    • In-stock
      (2R,3S)-tert-Butyl 6-oxo-2,3-diphenylmorpholine-4-carboxylate|CS-W002317
      112741-49-8

    References

    • Williams, Robert M.; Sinclair, Peter J.; Zhai, Dongguan; Chen, Daimo Journal of the American Chemical Society, 1988 , vol. 110, # 5 p. 1547 - 1557
  • Route2

    References

    • Synlett, , # 4 art. no. Y04304ST, p. 693 - 696
  • Route3
    • In-stock
      Di-tert-butyl dicarbonate|CS-0017817
      24424-99-5
    • Ethyl 2-(((1S,2R)-2-Hydroxy-1,2-diphenylethyl)amino)acetate|CS-0765478
      100678-82-8
    • ~82%
    • In-stock
      (2R,3S)-tert-Butyl 6-oxo-2,3-diphenylmorpholine-4-carboxylate|CS-W002317
      112741-49-8

    References

    • Yeo, David J.; Warriner, Stuart L.; Wilson, Andrew J. Chemical Communications, 2013 , vol. 49, # 80 p. 9131 - 9133

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   55.84
  • LogP   4.2629
  • H_Acceptors   4
  • H_Donors   0
  • Rotatable_Bonds   2

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