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CS-W001157 4
Total: USD 88.00

3-(3-Pyridinyl)acrylic acid

  • CAS No. 1126-74-5

  • Cat. No. CS-0031477
  • Purity≥97%
  • MDL No.MFCD00006410

*For research and further manufacturing use only, not for direct human use.

3-(3-Pyridinyl)acrylic acid|CS-0031477

Structure of 1126-74-5

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General Information

  • CAS No. 1126-74-5
  • Cat. No. CS-0031477
  • Purity ≥97%
  • MDL No. MFCD00006410
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₇NO₂
  • Molecular Weight 149.15
  • Synonym(s) 3-Pyridineacrylic Acid
  • SMILES O=C(/C=C/C1=CC=CN=C1)O

Description

3-(3-Pyridinyl)acrylic acid integrates a pyridine ring with an α,β-unsaturated carboxylic acid moiety, enabling direct conjugation in cross-coupling and bioconjugation workflows. The electron-deficient olefin facilitates Michael additions, while the pendant carboxylic acid offers versatile derivatization potential under standard conditions.

Application

3-(3-Pyridinyl)acrylic acid serves as a versatile building block for constructing bioactive heterocyclic scaffolds and conjugated systems. Its acrylic acid functionality enables direct participation in Michael additions, esterifications, and amidations, while the pendant 3-pyridyl group offers enhanced solubility and potential for metal coordination. The compound exhibits bench stability and facilitates straightforward purification, making it well-suited for iterative synthesis in medicinal chemistry and materials development.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   50.19
  • LogP   1.1794
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   2

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