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CS-W001157 4
Total: USD 88.00

1H-Pyrrole-2,3-dicarboxylic acid

  • CAS No. 1125-32-2

  • Cat. No. CS-0155548
  • Molecule weight155.11
  • Purity≥98%
  • MDL No.MFCD09991931

*For research and further manufacturing use only, not for direct human use.

1H-Pyrrole-2,3-dicarboxylic acid|CS-0155548

Structure of 1125-32-2

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General Information

  • CAS No. 1125-32-2
  • Cat. No. CS-0155548
  • Purity ≥98%
  • MDL No. MFCD09991931
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₅NO₄
  • Molecular Weight 155.11
  • Synonym(s) pyrrole-2,3-dicarboxylic acid
  • SMILES C1=CNC(=C1C(=O)O)C(=O)O

Description

1H-Pyrrole-2,3-dicarboxylic acid features a rigid, electron-rich pyrrole core with two adjacent carboxylic acid groups, enabling robust coordination in metal complexes and serving as a key scaffold for heterocyclic synthesis. This bench-stable compound integrates readily into pharmaceutical intermediates and functional materials.

Application

1H-Pyrrole-2,3-dicarboxylic acid serves as a versatile scaffold for the synthesis of heterocyclic compounds and pharmaceutical intermediates. Its dual carboxylic acid functionality enables straightforward derivatization via amide, ester, or hydrazide formation, while maintaining stability under standard bench conditions. The molecule functions effectively in coupling reactions and serves as a key building block in the construction of bioactive pyrrole-based architectures.

Synthesis

  • Route1
    • null|null
      89909-41-1
    • ~%
    • In-stock
      1H-Pyrrole-2,3-dicarboxylic acid|CS-0155548
      1125-32-2

    References

    • Gazzetta Chimica Italiana, , vol. 86, p. 757,762
  • Route2

    References

    • Tetrahedron, , vol. 51, # 20 p. 5913 - 5920
  • Route3

    References

    • Tetrahedron, , vol. 51, # 20 p. 5913 - 5920

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   90.39
  • LogP   0.4111
  • H_Acceptors   2
  • H_Donors   3
  • Rotatable_Bonds   2

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