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CS-W001157 4
Total: USD 88.00

4-Ethylcatechol

  • CAS No. 1124-39-6

  • Cat. No. CS-0309130
  • Purity≥95%
  • MDL No.MFCD00015847

*For research and further manufacturing use only, not for direct human use.

4-Ethylcatechol|CS-0309130

Structure of 1124-39-6

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General Information

  • CAS No. 1124-39-6
  • Cat. No. CS-0309130
  • Purity ≥95%
  • MDL No. MFCD00015847
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₁₀O₂
  • Molecular Weight 138.17
  • Synonym(s) None
  • SMILES OC1=CC=C(CC)C=C1O

Description

4-Ethylcatechol features a catechol core substituted with an ethyl group at the para position, delivering enhanced lipophilicity and stability compared to unsubstituted catechols. This structural modification improves solubility in organic media while preserving redox-active functionality, enabling its use in polymer synthesis, metal chelation studies, and as a building block for bioactive molecules under standard bench conditions.

Application

4-Ethylcatechol serves as a versatile building block in synthetic organic chemistry, enabling the construction of bioactive heterocycles and pharmaceutical intermediates. Its ortho-dihydroxy functionality facilitates metal-catalyzed coupling reactions and oxidation-sensitive transformations, while the ethyl substituent provides tunable steric and electronic properties. The compound exhibits good bench stability and compatibility with standard protecting group strategies, making it well-suited for iterative synthesis workflows in medicinal chemistry and process development.

Synthesis

  • Route1

    References

    • Guazzaroni, Melissa; Crestini, Claudia; Saladino, Raffaele Bioorganic and Medicinal Chemistry, 2012 , vol. 20, # 1 p. 157 - 166
  • Route2
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      4-Ethylcatechol|CS-0309130
      1124-39-6

    References

    • Hwu, Jih Ru; Wong, Fung Fuh; Huang, Jiann-Jyh; Tsay, Shwu-Chen Journal of Organic Chemistry, 1997 , vol. 62, # 12 p. 4097 - 4104
  • Route3
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      1398242-03-9

    References

    • Bioorganic and Medicinal Chemistry, , vol. 20, # 14 p. 4364 - 4370

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS05,GHS07
Signal Word : Danger
UN#: 1759
Class : 8
Packing Group : Ⅲ
Hazard Statements : H302-H315-H318-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   40.46
  • LogP   1.6602
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   1

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