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CS-W001157 4
Total: USD 88.00

6-Bromothiazolo[4,5-b]pyrazin-2-amine

  • CAS No. 112342-72-0

  • Cat. No. CS-0040876
  • Purity≥98%
  • MDL No.MFCD09909710

*For research and further manufacturing use only, not for direct human use.

6-Bromothiazolo[4,5-b]pyrazin-2-amine|CS-0040876

Structure of 112342-72-0

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General Information

  • CAS No. 112342-72-0
  • Cat. No. CS-0040876
  • Purity ≥98%
  • MDL No. MFCD09909710
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₃BrN₄S
  • Molecular Weight 231.07
  • Synonym(s) 2-Amino-6-bromothiazolo[4,5-B]pyrazine
  • SMILES NC1=NC2=NC=C(Br)N=C2S1

Synthesis

  • Route1
    • Ethyl (6-bromothiazolo[4,5-b]pyrazin-2-yl)carbamate|CS-0746737
      112342-70-8
    • ~92%
    • In-stock
      6-Bromothiazolo[4,5-b]pyrazin-2-amine|CS-0040876
      112342-72-0

    References

    • Shionogi and Co., Ltd. Patent: EP2351744 A1, 2011 ; Location in patent: Page/Page column 74 ;
  • Route2
    • Thiazolo[4,5-b]pyrazin-2-amine|CS-0076029
      112342-71-9
    • ~14%
    • In-stock
      6-Bromothiazolo[4,5-b]pyrazin-2-amine|CS-0040876
      112342-72-0

    References

    • Koren, Bozidar; Stanovnik, Branko; Tisler, Miha Heterocycles, 1987 , vol. 26, # 3 p. 689 - 697
  • Route3
    • N-(Ethoxy(hydroxy)methylene)-N'-(pyrazin-2-yl)carbamimidothioic acid|CS-1652895
      56406-73-6
    • ~%
    • In-stock
      6-Bromothiazolo[4,5-b]pyrazin-2-amine|CS-0040876
      112342-72-0

    References

    • Heterocycles, , vol. 26, # 3 p. 689 - 697

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   64.69
  • LogP   1.431
  • H_Acceptors   5
  • H_Donors   1
  • Rotatable_Bonds   0

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