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CS-W001157 4
Total: USD 88.00

4,4-Dimethylpiperidine-2,6-dione

  • CAS No. 1123-40-6

  • Cat. No. CS-W022042
  • Purity≥98%
  • MDL No.MFCD00006671

*For research and further manufacturing use only, not for direct human use.

4,4-Dimethylpiperidine-2,6-dione|CS-W022042

Structure of 1123-40-6

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General Information

  • CAS No. 1123-40-6
  • Cat. No. CS-W022042
  • Purity ≥98%
  • MDL No. MFCD00006671
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₁₁NO₂
  • Molecular Weight 141.17
  • Synonym(s) 4,4-Dimethyl-2,6-piperidinedione
  • SMILES CC1(C)CC(=O)NC(=O)C1

Application

4,4-Dimethylpiperidine-2,6-dione serves as a versatile building block in medicinal chemistry, enabling efficient access to saturated heterocyclic scaffolds. Its diketone functionality facilitates nucleophilic addition and condensation reactions, while the sterically hindered quaternary center enhances metabolic stability. The compound exhibits excellent bench stability and ease of purification, making it well-suited for modular synthesis workflows in API development.

Synthesis

  • Route1

    References

    • Young, Michael C.; Liew, Erica; Ashby, Jonathan; McCoy, Kelsi E.; Hooley, Richard J. Chemical Communications, 2013 , vol. 49, # 57 p. 6331 - 6333 Title/Abstract Full Text View citing articles Show Details Young, Michael C.; Liew, Erica; Ashby, Jonathan; McCoy, Kelsi E.; Hooley, Richard J. Chemical Communications, 2013 , vol. 49, # 56 p. 6331 - 6333
  • Route2
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      38597-82-9
    • ~%
    • In-stock
      4,4-Dimethylpiperidine-2,6-dione|CS-W022042
      1123-40-6

    References

    • Chabudzinski, Zenon; Czuba, Wladyslaw; Lipnicka, Urszula; Rykowski, Zbigniew; Sedzik-Hibner, Dorota; Wrzesien, Justyna Polish Journal of Chemistry, 1980 , vol. 54, # 7/8 p. 1459 - 1463
  • Route3
    • null|null
      854704-89-5
    • ~%
    • In-stock
      4,4-Dimethylpiperidine-2,6-dione|CS-W022042
      1123-40-6

    References

    • Journal of the Chemical Society, , vol. 99, # 431 p. 432,433,434

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H317-H319-H335
Precautionary Statements : P261-P264-P270-P271-P272-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   46.17
  • LogP   0.4492
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   0

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