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CS-W001157 4
Total: USD 88.00

4-Methylpyridazine

  • CAS No. 1120-88-3

  • Cat. No. CS-W019241
  • Purity≥97%
  • MDL No.MFCD00011594

*For research and further manufacturing use only, not for direct human use.

4-Methylpyridazine|CS-W019241

Structure of 1120-88-3

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General Information

  • CAS No. 1120-88-3
  • Cat. No. CS-W019241
  • Purity ≥97%
  • MDL No. MFCD00011594
  • Storage -20°C, sealed storage, away from moisture
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₆N₂
  • Molecular Weight 94.11
  • Synonym(s) 4-METHYLPYRADIZINE
  • SMILES C1=C(C)C=NN=C1

Description

4-Methylpyridazine features a methyl-substituted pyridazine core, offering enhanced electron density at the ring system. This bench-stable heterocycle serves as a key scaffold in medicinal chemistry, enabling efficient integration into bioactive molecules through selective functionalization at nitrogen sites.

Application

4-Methylpyridazine serves as a versatile heterocyclic building block in medicinal chemistry and materials science. Its pyridazine core enables diverse functionalization, particularly at the 3- and 5-positions, while the methyl group enhances metabolic stability and modulates electronic properties. The compound exhibits good bench stability and compatibility with standard coupling reactions, facilitating efficient synthesis of pharmacologically relevant scaffolds.

Synthesis

  • Route1

    References

    • Heterocycles, , vol. 22, # 6 p. 1395 - 1402
  • Route2
    • In-stock
      Pyridazine|CS-W007494
      289-80-5
    • null|null
      75-91-2
    • ~20%
    • In-stock
      4-Methylpyridazine|CS-W019241
      1120-88-3
    • 3,4-Dimethylpyridazine|CS-0484830
      68206-10-0
    • 4,5-Dimethylpyridazine|CS-0540010
      38283-35-1
    • null|null
      22863-59-8

    References

    • Heterocycles, , vol. 22, # 6 p. 1395 - 1402
  • Route3
    • In-stock
      Pyridazine|CS-W007494
      289-80-5
    • null|null
      64-19-7
    • ~17%
    • In-stock
      4-Methylpyridazine|CS-W019241
      1120-88-3
    • 3,4-Dimethylpyridazine|CS-0484830
      68206-10-0
    • 4,5-Dimethylpyridazine|CS-0540010
      38283-35-1
    • null|null
      22863-59-8

    References

    • Heterocycles, , vol. 22, # 6 p. 1395 - 1402

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   25.78
  • LogP   0.78502
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   0

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