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CS-W001157 4
Total: USD 88.00

Norquetiapine dihydrochloride

  • CAS No. 111974-74-4

  • Cat. No. CS-W021295
  • Purity≥98%
  • MDL No.MFCD08703302

*For research and further manufacturing use only, not for direct human use.

Norquetiapine dihydrochloride|CS-W021295

Structure of 111974-74-4

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General Information

  • CAS No. 111974-74-4
  • Cat. No. CS-W021295
  • Purity ≥98%
  • MDL No. MFCD08703302
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₇H₁₉Cl₂N₃S
  • Molecular Weight 368.32
  • Synonym(s) N-Desalkylquetiapine (dihydrochloride)
  • SMILES C12=CC=CC=C1N=C(C3=CC=CC=C3S2)N4CCNCC4.Cl.Cl

Application

11-(1-Piperazinyl)-dibenzo[b,f][1,4]thiazepine dihydrochloride serves as a versatile heterocyclic building block for medicinal chemistry campaigns targeting CNS disorders. The piperazinyl moiety enhances solubility and modulates pharmacokinetic properties, while the dibenzo-thiazepine core provides structural rigidity suitable for receptor-targeted ligand design. Its dihydrochloride salt form ensures excellent bench stability, ease of handling, and compatibility with standard synthetic workflows involving amine functionalization or metal-catalyzed coupling reactions.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   27.63
  • LogP   3.9783
  • H_Acceptors   4
  • H_Donors   1
  • Rotatable_Bonds   0

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