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CS-W001157 4
Total: USD 88.00

Biotin-EDA

  • CAS No. 111790-37-5

  • Cat. No. CS-0116326
  • Purity≥97%
  • MDL No.MFCD09839905

*For research and further manufacturing use only, not for direct human use.

Biotin-EDA|CS-0116326

Structure of 111790-37-5

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General Information

  • CAS No. 111790-37-5
  • Cat. No. CS-0116326
  • Purity ≥97%
  • MDL No. MFCD09839905
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₂H₂₂N₄O₂S
  • Molecular Weight 286.39
  • Synonym(s) None
  • SMILES O=C(NCCN)CCCC[C@@H]1SC[C@]([C@]1([H])N2)([H])NC2=O

Description

Biotin-EDA features a bifunctional linker with an amine-reactive NHS ester and a biotin moiety, enabling efficient conjugation to primary amines on proteins or antibodies. This reagent facilitates robust detection and purification through high-affinity streptavidin binding, ideal for immunoassays, pull-down assays, and bioconjugation workflows under standard conditions.

Synthesis

  • Route1
    • In-stock
      Biotin NHS|CS-5714
      35013-72-0
    • null|null
      107-15-3
    • ~97%
    • In-stock
      Biotin-EDA|CS-0116326
      111790-37-5

    References

    • Yamada, Michio; Harada, Kenji; Maeda, Yutaka; Hasegawa, Tadashi New Journal of Chemistry, 2013 , vol. 37, # 11 p. 3762 - 3769
  • Route2
    • null|null
      107-15-3
    • In-stock
      Biotin methyl ester|CS-0160775
      608-16-2
    • ~99%
    • In-stock
      Biotin-EDA|CS-0116326
      111790-37-5

    References

    • Tao, Lei; Geng, Jin; Chen, Gaojian; Xu, Yingjian; Ladmiral, Vincent; Mantovani, Giuseppe; Haddleton, David. M. Chemical Communications, 2007 , # 33 p. 3441 - 3443
  • Route3
    • N-Boc-Biotinylethylenediamine|CS-0659017
      225797-46-6
    • ~%
    • In-stock
      Biotin-EDA|CS-0116326
      111790-37-5

    References

    • Bioorganic and medicinal chemistry, , vol. 11, # 2 p. 235 - 249

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   96.25
  • LogP   -0.2129
  • H_Acceptors   4
  • H_Donors   4
  • Rotatable_Bonds   7

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