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Structure of 1114573-41-9
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5-Bromo-1-(cyclopropylmethyl)-1,2-dihydropyridin-2-one features a brominated pyridinone core paired with a cyclopropylmethyl substituent, delivering enhanced electrophilic reactivity and steric control. This bench-stable scaffold integrates readily into cross-coupling and cyclization sequences, enabling efficient access to functionalized heterocycles in medicinal chemistry and materials synthesis.
5-Bromo-1-(cyclopropylmethyl)-1,2-dihydropyridin-2-one serves as a versatile building block for the synthesis of substituted pyridine derivatives and heterocyclic scaffolds. Its bromine substituent enables facile palladium-catalyzed cross-coupling reactions, while the dihydropyridinone core provides a stable platform for further functionalization. The cyclopropylmethyl group enhances metabolic stability and modulates lipophilicity, offering favorable properties for medicinal chemistry applications. This compound exhibits excellent bench stability and is readily purified by standard chromatographic methods, facilitating integration into multi-step synthetic sequences.
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GHS Pictogram :
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GHS No : GHS06
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Signal Word : Danger
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UN#: 2811
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Class : 6.1
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Packing Group : Ⅲ
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Hazard Statements : H301-H311-H331
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P361-P405-P501
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Lot numbers can be found on the outside label of a product: