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CS-W001157 4
Total: USD 88.00

4-Oxaspiro[2.4]heptan-7-one

  • CAS No. 111291-58-8

  • Cat. No. CS-0567737
  • Molecule weight112.13
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

4-Oxaspiro[2.4]heptan-7-one|CS-0567737

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General Information

  • CAS No. 111291-58-8
  • Cat. No. CS-0567737
  • Purity ≥97%
  • MDL No. None
  • Storage 4°C, sealed storage, away from moisture
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₈O₂
  • Molecular Weight 112.13
  • Synonym(s) None
  • SMILES O=C1CCOC21CC2

Description

4-Oxaspiro[2.4]heptan-7-one features a rigid, fused spirocyclic architecture combining a tetrahydrofuran ring with a cyclopentanone moiety. This structural motif imparts high conformational stability and serves as a valuable scaffold in synthetic medicinal chemistry, particularly for probing bioactive molecular geometries.

Application

4-Oxaspiro[2.4]heptan-7-one serves as a versatile, bench-stable building block for the synthesis of spirocyclic heterocycles and natural product analogs. Its fused oxirane and ketone functionalities enable controlled ring-opening reactions and facilitate regioselective functionalization, supporting applications in medicinal chemistry and process development. The scaffold exhibits excellent compatibility with standard synthetic protocols and offers straightforward purification via chromatography or crystallization.

Safety Information

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GHS Pictogram : N/A
GHS No : N/A
Signal Word : N/A
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : N/A
Precautionary Statements : N/A

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Computational Chemistry Data

  • TPSA   26.3
  • LogP   0.5084
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   0

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