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Structure of 1105039-88-0
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This pyrazole scaffold integrates a methoxybenzyl group and a boronate ester for efficient cross-coupling. The tetramethyl-dioxaborolane moiety enables stable, room-temperature Suzuki-Miyaura reactions, while the para-methoxy substituent enhances solubility and electronic modulation. Designed for modular synthesis in medicinal chemistry and materials science applications.
1-(4-Methoxybenzyl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole serves as a versatile boronate building block for Suzuki-Miyaura cross-coupling reactions. The pyrazole core provides structural stability and bioisostropic potential, while the 4-methoxybenzyl group offers orthogonal protection and facilitates purification. The pinacol boronate moiety enables reliable coupling under mild conditions, with excellent functional group tolerance and bench stability, making it well-suited for iterative synthesis of complex heterocyclic scaffolds in medicinal chemistry and process development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H312-H332
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P501
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Lot numbers can be found on the outside label of a product: