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Structure of 110351-94-5
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Exatecan Intermediate 1 features a sterically hindered pyrrolidine core paired with a reactive trifluoromethyl ketone moiety, enabling selective coupling in late-stage functionalization. This bench-stable scaffold integrates seamlessly into complex molecular architectures under standard conditions.
Exatecan Intermediate 1 serves as a key building block in the synthesis of exatecan-based anticancer agents, enabling efficient construction of the core indoline scaffold. Its well-defined reactivity profile facilitates selective functionalization under mild conditions, with demonstrated compatibility across standard coupling and cyclization protocols. Bench-stable and readily purified by chromatography, it supports scalable synthesis and integration into complex molecular architectures relevant to medicinal chemistry campaigns.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: