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CS-W001157 4
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(1-Ethyl-1H-pyrazol-5-yl)boronic acid

  • CAS No. 1095080-54-8

  • Cat. No. CS-0028760
  • Purity≥95%
  • MDL No.MFCD03419491

*For research and further manufacturing use only, not for direct human use.

(1-Ethyl-1H-pyrazol-5-yl)boronic acid|CS-0028760

Structure of 1095080-54-8

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General Information

  • CAS No. 1095080-54-8
  • Cat. No. CS-0028760
  • Purity ≥95%
  • MDL No. MFCD03419491
  • Storage -20°C, sealed storage, away from moisture
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₉BN₂O₂
  • Molecular Weight 139.95
  • Synonym(s) B-(1-Ethyl-1H-pyrazol-5-yl)boronic acid
  • SMILES CCN1N=CC=C1B(O)O

Description

This boronate moiety integrates readily into Suzuki-Miyaura cross-coupling reactions, delivering functionalized pyrazoles with high efficiency. The ethyl substitution enhances solubility and stability under standard conditions, enabling straightforward incorporation into complex molecular architectures.

Application

(1-Ethyl-1H-pyrazol-5-yl)boronic acid serves as a versatile building block in Suzuki-Miyaura cross-coupling reactions, enabling efficient C–C bond formation under mild conditions. Its pyrazole core provides enhanced stability and solubility compared to simpler boronic acids, while the ethyl substituent improves handling and reduces protodeboronation. The compound exhibits excellent functional group tolerance and facilitates the synthesis of biologically relevant heterocyclic scaffolds in medicinal chemistry and materials science applications.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   58.28
  • LogP   -1.4172
  • H_Acceptors   4
  • H_Donors   2
  • Rotatable_Bonds   2

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