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CS-W001157 4
Total: USD 88.00

1,4-Dioxaspiro[4.4]nonan-7-ol

  • CAS No. 109459-57-6

  • Cat. No. CS-0029559
  • Molecule weight144.17
  • Purity≥95%
  • MDL No.MFCD28502539

*For research and further manufacturing use only, not for direct human use.

1,4-Dioxaspiro[4.4]nonan-7-ol|CS-0029559

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General Information

  • CAS No. 109459-57-6
  • Cat. No. CS-0029559
  • Purity ≥95%
  • MDL No. MFCD28502539
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₁₂O₃
  • Molecular Weight 144.17
  • Synonym(s) 3-hydroxy-cyclopentanone ethylene acetal
  • SMILES OC(CC1)CC21OCCO2

Description

1,4-Dioxaspiro[4.4]nonan-7-ol features a rigid spirocyclic framework with dual ether linkages, offering enhanced stability and defined stereochemistry. This bench-stable, moisture-tolerant scaffold integrates readily into complex molecular architectures, enabling efficient access to constrained heterocyclic systems in synthetic and medicinal chemistry applications.

Application

1,4-Dioxaspiro[4.4]nonan-7-ol serves as a versatile bicyclic scaffold for medicinal chemistry and synthetic intermediates, offering stable stereochemical control and orthogonal functionalization at the hydroxyl-bearing carbon. Its rigid spirocyclic framework enhances conformational preorganization, facilitating efficient incorporation into bioactive molecules. The compound exhibits excellent bench stability, tolerates common protecting group manipulations, and participates reliably in standard coupling and derivatization reactions, making it a practical building block for complex molecular architectures.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302
Precautionary Statements : P264-P270-P330-P501

Quality Control

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Computational Chemistry Data

  • TPSA   38.69
  • LogP   0.2743
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   0

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