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CS-W001157 4
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Isoquinolin-7-ylboronic acid

  • CAS No. 1092790-21-0

  • Cat. No. CS-0006100
  • Purity≥95%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

Isoquinolin-7-ylboronic acid|CS-0006100

Structure of 1092790-21-0

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General Information

  • CAS No. 1092790-21-0
  • Cat. No. CS-0006100
  • Purity ≥95%
  • MDL No. None
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₈BNO₂
  • Molecular Weight 172.98
  • Synonym(s) Isoquinoline-7-boronic acid
  • SMILES OB(C1=CC2=CN=CC=C2C=C1)O

Description

Isoquinolin-7-ylboronic acid delivers a rigid, electron-deficient boronate moiety positioned for direct incorporation into Suzuki-Miyaura cross-coupling reactions. This bench-stable reagent integrates efficiently with aryl halides to construct complex heteroaryl architectures under standard conditions.

Application

Isoquinolin-7-ylboronic acid serves as a versatile building block in palladium-catalyzed cross-coupling reactions, enabling efficient construction of biaryl scaffolds. Its bench-stable nature and compatibility with diverse functional groups facilitate reliable synthesis of complex heterocyclic architectures. The boronic acid moiety reacts predictably with aryl halides and triflates under standard Suzuki-Miyaura conditions, making it a practical choice for medicinal chemistry and materials science applications.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   53.35
  • LogP   -0.0854
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   1

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