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Structure of 109216-61-7
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Methyl 2-methyl-2H-indazole-3-carboxylate features a sterically hindered indazole core with a methyl group at the 2-position, enhancing stability and modulating electronic properties. The ester functionality enables direct use in cross-coupling reactions or hydrolysis to access carboxylic acid derivatives. This compound serves as a key intermediate in medicinal chemistry for developing kinase inhibitors and bioactive heterocycles.
Methyl 2-methyl-2H-indazole-3-carboxylate serves as a versatile building block for the synthesis of indazole-based pharmaceuticals and agrochemicals. The ester group enables straightforward derivatization, while the 2-methyl substitution enhances stability and modulates reactivity. It functions effectively in Pd-catalyzed cross-coupling reactions and participates in electrophilic functionalization at the C2 position, offering reliable access to substituted indazoles under standard bench conditions.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: