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Structure of 1088994-22-2
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5-Methyl-2-(pyrimidin-2-yl)benzoic acid features a fused aromatic core combining a methyl-substituted benzoic acid with a pyrimidine ring, enabling strong π-stacking and hydrogen-bonding interactions. This scaffold delivers enhanced solubility and stability in polar solvents, facilitating direct integration into medicinal chemistry campaigns targeting kinase inhibitors and GPCR modulators.
5-Methyl-2-(pyrimidin-2-yl)benzoic acid serves as a versatile building block in medicinal chemistry, enabling the construction of biologically relevant heterocyclic scaffolds. Its carboxylic acid functionality facilitates direct amidation, esterification, and coupling reactions, while the pyrimidine ring provides enhanced metabolic stability and hydrogen-bonding capacity. The methyl group offers a site for further functionalization, and the molecule exhibits excellent bench stability and ease of purification, making it well-suited for high-throughput synthesis and process development workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: