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Structure of 108354-78-5
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Methyl 2-amino-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylate features a saturated thiophene core with a strategically positioned amino group and ester functionality. This scaffold integrates readily into medicinal chemistry campaigns, offering enhanced solubility and metabolic stability compared to aromatic analogs. The compound serves as a key intermediate in the synthesis of bioactive heterocycles, particularly within kinase inhibitor and CNS-targeted drug discovery programs.
Methyl 2-amino-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylate serves as a versatile heterocyclic building block for medicinal chemistry and process development. The molecule combines a readily functionalizable amine, a stable tetrahydrothiophene core, and a methyl ester group compatible with standard transformations. It facilitates efficient synthesis of substituted benzothiophenes and scaffolds relevant to kinase inhibitors and CNS-targeted therapeutics. Bench-stable and amenable to purification by standard chromatography or recrystallization, it enables robust downstream derivatization in multi-step sequences.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: