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Structure of 1083224-23-0
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5-(2,4-Difluorophenyl)isoxazole-3-carboxylic acid features a rigid isoxazole core flanked by a difluorophenyl group and a carboxylic acid handle, enabling direct integration into bioactive scaffolds. This electron-deficient heterocycle offers enhanced metabolic stability and favorable binding interactions in medicinal chemistry applications.
5-(2,4-Difluorophenyl)isoxazole-3-carboxylic acid serves as a versatile building block in medicinal chemistry, enabling the construction of bioactive heterocyclic scaffolds. The isoxazole core exhibits favorable metabolic stability and functions as a key pharmacophore in kinase inhibitor and CNS-targeted compound development. Its carboxylic acid group facilitates direct conjugation or derivatization via amide, ester, or amidation reactions, while the 2,4-difluorophenyl substituent enhances membrane permeability and modulates electronic properties. Bench-stable and readily purified by recrystallization, it supports scalable synthesis in API research workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P280-P302+P352
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Lot numbers can be found on the outside label of a product: