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Structure of 1083057-14-0
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tert-Butyl 3-(6-amino-3-methylpyridin-2-yl)benzoate features a strategically positioned amino group on a methyl-substituted pyridine ring, enabling direct coupling in late-stage functionalization. The tert-butyl ester serves as a robust, moisture-tolerant handle for selective deprotection under mild acidic conditions. This scaffold integrates electron-rich heterocyclic and aromatic moieties, facilitating efficient access to complex pharmacophores in medicinal chemistry.
tert-Butyl 3-(6-amino-3-methylpyridin-2-yl)benzoate serves as a versatile building block for the synthesis of bioactive heterocycles, enabling efficient late-stage functionalization via the pendant amine and ester groups. The molecule exhibits excellent bench stability, facilitates straightforward deprotection under mild acidic conditions, and supports diverse coupling reactions, making it well-suited for medicinal chemistry campaigns requiring modular scaffold elaboration.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: