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Structure of 1082872-21-6
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4-Bromo-1-(methylsulfonyl)piperidine features a brominated piperidine core with a polar methylsulfonyl group, enhancing solubility and enabling diverse functionalization. This bench-stable scaffold integrates readily into medicinal chemistry campaigns, serving as a key building block for targeted bioactive molecules.
4-Bromo-1-(methylsulfonyl)piperidine serves as a versatile building block in medicinal chemistry, enabling efficient late-stage functionalization via palladium-catalyzed cross-coupling. The bromide facilitates C–C bond formation under standard Suzuki or Negishi conditions, while the methylsulfonyl group enhances solubility and provides a polar handle for structure-activity optimization. Bench-stable and readily purified by column chromatography, it functions effectively in the synthesis of bioactive heterocycles and API intermediates.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: