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1H-Pyrrolo[3,2-c]pyridine-7-carboxylic acid

  • CAS No. 1082040-92-3

  • Cat. No. CS-0052487
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

1H-Pyrrolo[3,2-c]pyridine-7-carboxylic acid|CS-0052487

Structure of 1082040-92-3

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General Information

  • CAS No. 1082040-92-3
  • Cat. No. CS-0052487
  • Purity ≥97%
  • MDL No. None
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₆N₂O₂
  • Molecular Weight 162.15
  • Synonym(s) 5-Azaindole-7-carboxylic acid
  • SMILES OC(=O)C1=C2NC=CC2=CN=C1

Description

1H-Pyrrolo[3,2-c]pyridine-7-carboxylic acid delivers a rigid, electron-deficient heterocyclic scaffold ideal for medicinal chemistry applications. This compound integrates seamlessly into bioactive molecules, offering enhanced metabolic stability and predictable binding geometry in target-directed drug discovery.

Application

1H-Pyrrolo[3,2-c]pyridine-7-carboxylic acid serves as a versatile heterocyclic building block in medicinal chemistry, enabling direct incorporation into bioactive scaffolds due to its planar, nitrogen-rich core and carboxylic acid functionality. The molecule exhibits bench stability, facilitates efficient derivatization via amide coupling or esterification, and demonstrates compatibility with standard synthetic protocols, including Suzuki-Miyaura and Buchwald-Hartwig reactions, supporting rapid access to diverse analogs for structure-activity investigations.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   65.98
  • LogP   1.2611
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   1

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