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CS-W001157 4
Total: USD 88.00

COMU

  • CAS No. 1075198-30-9

  • Cat. No. CS-0043565
  • Purity≥96%
  • MDL No.MFCD11975052

*For research and further manufacturing use only, not for direct human use.

COMU|CS-0043565

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General Information

  • CAS No. 1075198-30-9
  • Cat. No. CS-0043565
  • Purity ≥96%
  • MDL No. MFCD11975052
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₂H₁₉F₆N₄O₄P
  • Molecular Weight 428.27
  • Synonym(s) 4-{{[(1-Cyano-2-ethoxy-2-oxoethylidene)-amino]-oxayl}-(dimethylamino)-methylene}-hexafluorophosphate morpholinium
  • SMILES CN(/C(O/N=C(C#N)/C(OCC)=O)=[N+]1CCOCC\1)C.F[P-](F)(F)(F)(F)F

Description

Bromo-PEG3-acid is a heterobifunctional, PEGylated crosslinker featuring a bromo group at one end and a carboxyl group at the other. The hydrophillic PEG linker facilitates solubility in biological applications. Bromo-PEG3-acid can be used for bioconjugation or as a building block for synthesis of small molecules, conjugates of small molecules and/or biomolecules, or other tool compounds for chemical biology and medicinal chemistry that require ligation. Examples of applications include its synthetic incorporation into antibody-drug conjugates or proteolysis-targeting chimeras (PROTAC molecules) for targeted protein degradation.

Safety Information

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GHS Pictogram :
GHS No : GHS02,GHS07
Signal Word : Danger
UN#: 1325
Class : 4.1
Packing Group : Ⅱ
Hazard Statements : H228-H315-H319
Precautionary Statements : P210-P240-P241-P264-P280-P302+P352-P362+P364-P370+P378

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Computational Chemistry Data

  • TPSA   87.16
  • LogP   2.78838
  • H_Acceptors   6
  • H_Donors   0
  • Rotatable_Bonds   3

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