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Structure of 1075184-01-8
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2-(Difluoromethyl)quinoline features a strategically positioned difluoromethyl group that enhances metabolic stability and modulates electronic properties within the quinoline scaffold. This substitution imparts improved lipophilicity and electron-withdrawing character, making it a valuable building block for medicinal chemistry applications. The molecule exhibits bench-stable handling characteristics and compatibility with standard synthetic protocols.
2-(Difluoromethyl)quinoline serves as a valuable building block in medicinal chemistry, offering a unique combination of electronic and steric properties. The difluoromethyl group enhances metabolic stability and modulates lipophilicity, while the quinoline core provides a versatile scaffold for further functionalization. It reacts predictably in standard coupling and electrophilic substitution reactions, enabling efficient access to complex heterocyclic systems. Its bench-stable nature and compatibility with common synthetic protocols make it ideal for iterative synthesis workflows in drug discovery.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P280-P302+P352
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Lot numbers can be found on the outside label of a product: