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CS-W001157 4
Total: USD 88.00

Buspirone impurity 9

  • CAS No. 1075-89-4

  • Cat. No. CS-0077659
  • Purity≥96%
  • MDL No.MFCD00023871

*For research and further manufacturing use only, not for direct human use.

Buspirone impurity 9|CS-0077659

Structure of 1075-89-4

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General Information

  • CAS No. 1075-89-4
  • Cat. No. CS-0077659
  • Purity ≥96%
  • MDL No. MFCD00023871
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₁₃NO₂
  • Molecular Weight 167.21
  • Synonym(s) None
  • SMILES O=C1NC(=O)CC2(C1)CCCC2

Application

8-Azaspiro[4.5]decane-7,9-dione serves as a rigid, bicyclic scaffold for medicinal chemistry campaigns, enabling the construction of diverse heterocyclic architectures. Its embedded ketone functionalities facilitate nucleophilic additions and reductive aminations, while the spirocyclic framework imparts conformational restraint. The compound exhibits good bench stability and compatibility with standard purification methods, making it a practical building block for targeted synthesis of bioactive molecules.

Synthesis

  • Route1

    References

    • Ishizumi; Kojima; Antoku Chemical and Pharmaceutical Bulletin, 1991 , vol. 39, # 9 p. 2288 - 2300

Safety Information

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GHS Pictogram :
GHS No : GHS06,GHS09
Signal Word : Danger
UN#: 2811
Class : 6.1
Packing Group : Ⅲ
Hazard Statements : H301-H411
Precautionary Statements : P264-P270-P273-P330-P391-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   46.17
  • LogP   0.9834
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   0

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